Clinical Study On Collagenase Treatment Of Lumbar Disc Herniation
Keywords
Collagenase, Intradiscal Injection, Epidural Injection, Dexamethasone, Lumbar Disc Herniation
Abstract
Abstract Objective To explore the efficacy and adverse reactions of different ways and methods of collagenase injection in the treatment of lumbar disc herniation. Methods: Collagenase 800U was diluted into 2 ml and injected into the posterior disc or epidural under the supervision of a TV There were 142 cases of collagenase alone, and 236 cases of combined injection of collagenase and dexamethasone in Group C. The results showed that statistically there was no significant difference in the excellent and good rates among the three groups, and the overall excellent and good rate was 86.5%. However, there were extremely significant differences in the reaction incidence rates among each group. Conclusion (1) The efficacy of epidural injection and intradiscal injection are the same; (2) The pain reaction of epidural injection is milder and less than that of intradiscal injection, and the pain reaction of adding dexamethasone is milder and less; (3) The epidural injection has milder and less pain reaction than intradiscal injection. Multiple disc herniations are more suitable
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Original research was done by Yin Lei, Hu Chuanliang, Hu Yuhua
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