Effects Of Surface Modification Of Pure Ti Implanted With Fluoride Ions On The Formation And Expression Of Type I Collagen In Osteoblasts
Keywords
Plasma Immersion Ion Implantation, Ti, Fluoride Ions, Osteoblasts, Type I Collagen
Abstract
plasma immersion ion implantation device was used to implant fluorine ions on the surface of pure Ti, and the surface morphology and chemical composition of the material were studied through SEM and XPS analysis. MG-63 osteoblasts were seeded on the surface of Ti samples before and after fluoride ion implantation. , Laser confocal microscopy was used to observe the effect of the material surface on the formation of type I collagen in osteoblast-like cells MG-63; reverse transcription polymerase chain reaction was used to detect the expression of type I collagen mRNA; Western blotting was used to detect the expression of type I collagen. The results showed that , TiF3 newly appeared on the surface of the Ti sample after fluoride ion implantation; and after MG-63 cells were cultured on the surface for 6, 24 and 48 hours respectively, the formation and expression of type I collagen were significantly higher than those on the pure Ti surface. Fluorine-containing surface modification layer It can improve the biocompatibility of Ti materials.
For further information of this article and research, feel free to contact our team for asssitance.
Original research was done by Liu Huiying, Wang Xuejin, Wang Langping, Wang Xiaofeng, Ai Hongjun
About ETChem
ETChem, a reputable Chinese Collagen factory manufacturer and supplier, is renowned for producing, stocking, exporting, and delivering the highest quality collagens. They include marine collagen, fish collagen, bovine collagen, chicken collagen, type I collagen, type II collagen and type III collagen etc. Their offerings, characterized by a neutral taste, and instant solubility attributes, cater to a diverse range of industries. They serve nutraceutical, pharmaceutical, cosmeceutical, veterinary, as well as food and beverage finished product distributors, traders, and manufacturers across Europe, USA, Canada, Australia, Thailand, Japan, Korea, Brazil, and Chile, among others.
ETChem specialization includes exporting and delivering tailor-made collagen powder and finished collagen nutritional supplements. Their extensive product range covers sectors like Food and Beverage, Sports Nutrition, Weight Management, Dietary Supplements, Health and Wellness Products, ensuring comprehensive solutions to meet all your protein needs.
As a trusted company by leading global food and beverage brands and Fortune 500 companies, ETChem reinforces China’s reputation in the global arena. For more information or to sample their products, please contact them and email karen(at)et-chem.com today.
