Clinical Observation Of 30% Supramolecular Salicylic Acid Combined With Humanoid Col-Lagen Bioremediation Dressing In The Treat-Ment Of Facial Seborrheic Dermatitis
Keywords
Supramolecular Salicylic Acid, Human Collagen Bioremediation Dressing, Facial Seborrheic Dermatitis
Abstract
Objective: To observe the effectiveness and safety of biorepair dressing (human-like collagen) combined with 30% supramolecular salicylic acid in the treatment of facial seborrheic dermatitis. Methods: 60 patients with facial seborrheic dermatitis admitted to the dermatology clinic of our hospital were selected, and all patients were divided into a control group (n = 30) and a treatment group (n = 30) using the random number table method. The control group was given 0.03 % Tacrolimus ointment was applied externally to the affected area, and the treatment group received external application of 0.03% Tacrolimus ointment + 30% supramolecular salicylic acid + human-like collagen biorepair dressing. The improvement of clinical symptoms and occurrence of adverse reactions will be observed one month after the end of treatment. Results: Before and after treatment, the differences in the scores of the three observation indicators of erythema, seborrhoea, and pruritus and the total score of the patients in the group were statistically significant (P < 0.01). The difference in the skin lesion area scores before and after treatment was not statistically significant (P > 0.05); before and after treatment, there was a statistically significant difference in the scores of the observation indicator skin lesion area and the total score of the patients in the group (P < 0.05); before treatment, there was no difference in the scores of the three observation indicators of erythema, seborrhoea, and pruritus. Statistical significance (P > 0.05); Comparing the scores of various observation indicators between groups after treatment, the decrease in scores of the three observation indicators of erythema, seborrhoea, and pruritus has significant statistical significance (P < 0.01), and the skin lesion area between groups The difference in scores was not statistically significant (P > 0.05). No serious adverse reactions occurred in the two groups of patients during or after treatment. Conclusion: 30% supramolecular salicylic acid combined with human-like collagen biorepair dressing is highly effective in treating facial seborrheic dermatitis with few adverse reactions and is suitable for clinical promotion. Objective: To observe the efficacy and safety of bioremediation dressing (human-like collagen) combined with 30% supramolecular salicylic acid in the treatment of facial seborrheic dermatitis. Methods: Selected 60 patients with facial seborrheic dermatitis admitted to the dermatology out-patient department of our hospital, and divided all patients into the control group (n = 30) and the treatment group (n = 30) by random number table, and the control group received 0.03% tacroli-mus ointment was applied externally to the affected area, and the treatment group was given 0.03% tacrolimus ointment + 30% supramolecular salicylic acid + human-like collagen bioremediation dressing. One month after the treatment, the patients were followed up to observe the improvement-ment of clinical symptoms and the occurrence of adverse reactions. Results: There were statistically significant differences in the scores of erythema, seborrhea and pruritus and total scores before and after treatment in the patients in the group (P < 0.01), but there was no significant difference in skin lesion area scores before and after treatment (P > 0.05); there was a statistically significant difference in the score of the skin lesion area and the total score of the patients in the group before and after treatment (P < 0.05). There was no statistically significant difference between the two groups (P > 0.05); comparing the scores of each observation index between the groups after treat-ment, the scores of the three observation indexes of erythema, seborrhea and pruritus decreased with statistical significance (P < 0.01). There was no significant difference in the score of mesothelial lesion area (P > 0.05). There were no serious adverse reactions in the two groups during and after treatment. Conclusion: 30% supramolecular salicylic acid combined with human-like collagen bio-remediation dressing has a higher effective rate and less adverse reactions in the treatment of facial seborrheic dermatitis, which is suitable
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Original research was done by Wang Jing, Zhu Xin, Fan Zhuo
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