Pachydermodactyly: 2 Cases Report And Literature Review Of Collagenosis Around The Proximal Interphalangeal Joint
Keywords
Pachydermodactyly, Collagen Deposition, Children Pachydermodactyly, Collagen Deposition, Children
Abstract
Objective: To explore the clinical characteristics of periproximal interphalangeal joint collagenosis (pachydermodactyly, PDD) and improve understanding of the disease. Methods: The clinical data of 2 children diagnosed with PDD were summarized and analyzed, and relevant literature was reviewed. Results: Both children showed swelling of the proximal interphalangeal joints of both hands without joint pain; physical examination showed fusiform enlargement of the sides of the affected joints, normal skin color and skin temperature, and no tenderness; there were no inflammatory indicators or immunological examinations. Abnormality; imaging examination showed swelling of the soft tissues of the proximal interphalangeal joints of both hands, without abnormal joint or bone changes; skin histopathological examination showed mild hyperplasia of squamous epithelium with hyperkeratosis, and hyperplasia of interstitial fibrocollagen tissue, and was diagnosed as PDD. , without treatment, all were followed up for more than 3 months, and there was no progression of joint symptoms. Conclusion: PDD is a rare benign disease that usually does not require special treatment. It needs to be clinically differentiated from inflammatory arthritis to avoid misdiagnosis and mistreatment. Objective: To explore the clinical features of pachydermodactyly (PDD) and to improve the under-standing of PDD. Methods: Summarize and analyze the clinical data of 2 cases of PDD and review relevant literature. Results: Both patients showed swelling of proximal interphalangeal joints of both hands without arthralgia. Physical examination showed fusiform enlargement of the lateral surface of the involved joint, normal skin color and temperature, no tenderness; inflammatory in-dex and immunological examination were normal; imaging examination showed swelling of the soft tissue of the proximal interphalangeal joints of both hands, without abnormal changes of joints and bones. Histopathological examination of the skin showed mild hyperplasia of squamous epithelium with hyperkeratosis and interstitial fibrous collagen hyperplasia, which was diagnosed as PDD. No treatment was given. All patients were followed up for more than 3 months, and the joint symptoms did not progress. Conclusion: PDD is a rare benign disease, usually without special treatment, clini-cal and inflammatory arthritis should be differentiated to avoid misdiagnosis and mistreatment.
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Original research was done by Chen Yu, Jiang Zhong, Shao Shihong, Chang Hong, Shao Leping, Lin Yi
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